8UZZ: Structure of TDP1 catalytic domain complexed with compound IB03

PDB ID: 8UZZDownload
MMDB ID: 252684
PDB Deposition Date: 2023/11/16
Updated in MMDB: 2024/09
Experimental Method:
x-ray diffraction
Resolution: 1.93  Å
Source Organism:
Similar Structures:
Biological Unit for 8UZZ: monomeric; determined by author
Molecular Components in 8UZZ
Label Count Molecule
Protein (1 molecule)
1
Tyrosyl-dna Phosphodiesterase 1
(Gene symbol: TDP1)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
(8M)-8-{2-[(fluorosulfonyl)oxy]phenyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(8M)-8-{2-[(fluorosulfonyl)oxy]phenyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
3
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
4
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303