8UXM: Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium and calmodulin

PDB ID: 8UXMDownload
MMDB ID: 238918
PDB Deposition Date: 2023/11/9
Updated in MMDB: 2023/11
Experimental Method:
electron microscopy
Resolution: 3.56  Å
Source Organism:
Similar Structures:
Biological Unit for 8UXM: dodecameric; determined by author
Molecular Components in 8UXM
Label Count Molecule
Proteins (12 molecules)
4
Calmodulin-1
(Gene symbol: CALM1)
Molecule annotation
4
Ryanodine Receptor 2
(Gene symbol: RYR2)
Molecule annotation
4
Peptidyl-prolyl Cis-trans Isomerase Fkbp1b
(Gene symbol: FKBP1B)
Molecule annotation
Chemicals and Non-standard biopolymers (32 molecules)
1
20
CALCIUM IONCALCIUM ION
2
4
ZINC IONZINC ION
3
8
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303