8UWZ: The structure of Raamsizumab in complex with VEGF121

PDB ID: 8UWZDownload
MMDB ID: 254888
PDB Deposition Date: 2023/11/8
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8UWZ: hexameric; determined by author
Molecular Components in 8UWZ
Label Count Molecule
Proteins (6 molecules)
2
Raamsizumab Heavy Chain
Molecule annotation
2
Raamsizumab Light Chain S1C Variant
Molecule annotation
2
Isoform Vegf121 of Vascular Endothelial Growth Factor A, Long Form
(Gene symbol: VEGFA)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranosebeta-D-mannopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303