8UW9: Structure of AKT1(E17K) with compound 4

PDB ID: 8UW9Download
MMDB ID: 251749
PDB Deposition Date: 2023/11/6
Updated in MMDB: 2024/09
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Lama glama▼
Similar Structures:
Biological Unit for 8UW9: dimeric; determined by author
Molecular Components in 8UW9
Label Count Molecule
Proteins (2 molecules)
1
Rac-alpha Serine/threonine-protein Kinase
Molecule annotation
1
Nb41
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
N-({4-[(2P)-2-(2-aminopyridin-3-yl)-5-phenyl-3H-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)-2-(2-fluoro-4-formyl-3-hydroxyphenyl)acetamideN-({4-[(2P)-2-(2-aminopyridin-3-yl)-5-phenyl-3H-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)-2-(2-fluoro-4-formyl-3-hydroxyphenyl)acetamide
2
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
4
SULFATE IONSULFATE ION
4
1
ZINC IONZINC ION
5
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303