8UVO: Human p97/VCP R155H mutant structure with a triazole inhibitor (NSC804515)

PDB ID: 8UVODownload
MMDB ID: 251287
PDB Deposition Date: 2023/11/3
Updated in MMDB: 2024/08
Experimental Method:
electron microscopy
Resolution: 3.22  Å
Source Organism:
Similar Structures:
Biological Unit for 8UVO: hexameric; determined by author
Molecular Components in 8UVO
Label Count Molecule
Proteins (6 molecules)
6
Transitional Endoplasmic Reticulum Atpase
(Gene symbol: VCP)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
12
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
2
6
N-[3-(2,5-difluoro-4-{[(4M)-5-(hexylsulfanyl)-4-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]methoxy}phenyl)prop-2-yn-1-yl]propanamideN-[3-(2,5-difluoro-4-{[(4M)-5-(hexylsulfanyl)-4-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]methoxy}phenyl)prop-2-yn-1-yl]propanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303