8UTB: Alpha7-nicotinic acetylcholine receptor bound to epibatidine and NS-1738

PDB ID: 8UTBDownload
MMDB ID: 243117
PDB Deposition Date: 2023/10/30
Updated in MMDB: 2025/05
Experimental Method:
electron microscopy
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8UTB: pentameric; determined by author
Molecular Components in 8UTB
Label Count Molecule
Proteins (5 molecules)
5
Neuronal Acetylcholine Receptor Subunit Alpha-7,soluble Cytochrome B562 Fusion
(Gene symbol: CHRNA7)
Molecule annotation
Chemicals and Non-standard biopolymers (50 molecules)
1
25
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
5
beta-D-mannopyranosebeta-D-mannopyranose
3
5
N-(5-chloro-2-hydroxyphenyl)-N'-[2-chloro-5-(trifluoromethyl)phenyl]ureaN-(5-chloro-2-hydroxyphenyl)-N'-[2-chloro-5-(trifluoromethyl)phenyl]urea
4
5
EPIBATIDINEEPIBATIDINE
5
5
(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en
6
5
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303