8USR: IL17A homodimer complexed to Compound 23

PDB ID: 8USRDownload
MMDB ID: 245000
PDB Deposition Date: 2023/10/29
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 1.83  Å
Source Organism:
Similar Structures:
Biological Unit for 8USR: dimeric; determined by author and by software (PISA)
Molecular Components in 8USR
Label Count Molecule
Proteins (2 molecules)
2
Interleukin-17a
(Gene symbol: IL17A)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
~{N}-[(2~{S})-1-[[(1~{S})-1-(8~{a}~{H}-imidazo[1,2-a]pyrimidin-2-yl)ethyl]amino]-1-oxidanylidene-4-phenyl-butan-2-yl]-4,5-bis(chloranyl)-1~{H}-pyrrole-2-carboxamide~{N}-[(2~{S})-1-[[(1~{S})-1-(8~{a}~{H}-imidazo[1,2-a]pyrimidin-2-yl)ethyl]amino]-1-oxidanylidene-4-phenyl-butan-2-yl]-4,5-bis(chloranyl)-1~{H}-pyrrole-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303