8UQ7: Alzheimer's disease PHF complexed with PET ligand MK-6240

PDB ID: 8UQ7Download
MMDB ID: 251743
PDB Deposition Date: 2023
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 2.31  Å
Source Organism:
Similar Structures:
Biological Unit for 8UQ7: hexameric; determined by author
Molecular Components in 8UQ7
Label Count Molecule
Proteins (6 molecules)
6
Microtubule-associated Protein TAU
(Gene symbol: MAPT)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
6
6-fluoro-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine6-fluoro-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303