8UO8: Structure of synaptic vesicle protein 2B with padsevonil

PDB ID: 8UO8Download
MMDB ID: 247325
PDB Deposition Date: 2023/10/19
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 8UO8: monomeric; determined by author and by software
Molecular Components in 8UO8
Label Count Molecule
Protein (1 molecule)
1
Synaptic Vesicle Glycoprotein 2B
(Gene symbol: SV2B)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
3
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
(4R)-4-(2-chloro-2,2-difluoroethyl)-1-{[(4R)-2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methyl}pyrrolidin-2-one(4R)-4-(2-chloro-2,2-difluoroethyl)-1-{[(4R)-2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methyl}pyrrolidin-2-one
3
1
1,2-DIDECANOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE]1,2-DIDECANOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE]
4
2
(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en
5
1
[(2R)-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-2-propanoyloxy-propyl] propanoate[(2R)-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-2-propanoyloxy-propyl] propanoate
6
1
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303