8UM5: X-ray structure of human SHIP1 Ptase-C2 domains covalently bound to TREAT-AD (TAD) compound TAD-58547

PDB ID: 8UM5Download
MMDB ID: 253914
PDB Deposition Date: 2023/10/17
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.86  Å
Source Organism:
Similar Structures:
Biological Unit for 8UM5: monomeric; determined by author
Molecular Components in 8UM5
Label Count Molecule
Protein (1 molecule)
1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
(Gene symbol: INPP5D)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
5-(1,4-oxazepan-4-yl)-6-propanoylpyridine-2-carbonitrile5-(1,4-oxazepan-4-yl)-6-propanoylpyridine-2-carbonitrile
2
3
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303