8UHB: Cryo-EM Structure of the Ro5256390-bound hTA1-Gs heterotrimer signaling complex

PDB ID: 8UHBDownload
MMDB ID: 241122
PDB Deposition Date: 2023/10/8
Updated in MMDB: 2024/05
Experimental Method:
electron microscopy
Resolution: 3.35  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 8UHB: pentameric; determined by author and by software
Molecular Components in 8UHB
Label Count Molecule
Proteins (5 molecules)
1
Soluble Cytochrome B562,beta-2 Adrenergic Receptor,trace Amine-associated Receptor 1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Nanobody 35
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2R,4S)-4-[(2S)-2-phenylbutyl]-1,3-oxazolidin-2-amine(2R,4S)-4-[(2S)-2-phenylbutyl]-1,3-oxazolidin-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303