8UG1: Crystal structure of KHK-C and compound 13

PDB ID: 8UG1Download
MMDB ID: 239531
PDB Deposition Date: 2023/10/5
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.99  Å
Source Organism:
Similar Structures:
Biological Unit for 8UG1: dimeric; determined by author and by software (PISA)
Molecular Components in 8UG1
Label Count Molecule
Proteins (2 molecules)
2
Ketohexokinase
(Gene symbol: KHK)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
2
{(2R)-1-[(4M)-4-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-6-(trifluoromethyl)pyrimidin-2-yl]azetidin-2-yl}methanol{(2R)-1-[(4M)-4-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-6-(trifluoromethyl)pyrimidin-2-yl]azetidin-2-yl}methanol
2
8
SULFATE IONSULFATE ION
3
3
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303