8UDU: The X-RAY co-crystal structure of human FGFR3 and Compound 17

PDB ID: 8UDUDownload
MMDB ID: 242437
PDB Deposition Date: 2023/9/29
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 1.737  Å
Source Organism:
Similar Structures:
Biological Unit for 8UDU: monomeric; determined by author
Molecular Components in 8UDU
Label Count Molecule
Protein (1 molecule)
1
Fibroblast Growth Factor Receptor 3
(Gene symbol: FGFR3)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
CHLORIDE IONCHLORIDE ION
2
1
3-[(6-chloro-1-cyclopropyl-1H-benzimidazol-5-yl)ethynyl]-1-[(3S,5S)-5-(methoxymethyl)-1-(prop-2-enoyl)pyrrolidin-3-yl]-5-(methylamino)-1H-pyrazole-4-carboxamide3-[(6-chloro-1-cyclopropyl-1H-benzimidazol-5-yl)ethynyl]-1-[(3S,5S)-5-(methoxymethyl)-1-(prop-2-enoyl)pyrrolidin-3-yl]-5-(methylamino)-1H-pyrazole-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303