8U8K: Co-crystal structure of phosphorylated ERK2 in complex with ERK1/2 inhibitor #8

PDB ID: 8U8KDownload
MMDB ID: 244712
PDB Deposition Date: 2023/9/18
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 8U8K: monomeric; determined by author
Molecular Components in 8U8K
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase 1
(Gene symbol: MAPK1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(4M)-4-{(4S)-3-[(2-chloropyridin-3-yl)methyl][1,2,4]triazolo[4,3-a]pyridin-7-yl}-N-(oxan-4-yl)pyrimidin-2-amine(4M)-4-{(4S)-3-[(2-chloropyridin-3-yl)methyl][1,2,4]triazolo[4,3-a]pyridin-7-yl}-N-(oxan-4-yl)pyrimidin-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303