8U7V: Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by GTP, ATP, IMP, and NAD+, interface-centered

PDB ID: 8U7VDownload
MMDB ID: 242131
PDB Deposition Date: 2023/9/15
Updated in MMDB: 2024/02
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8U7V: octameric; determined by author and by software
Molecular Components in 8U7V
Label Count Molecule
Proteins (8 molecules)
8
Inosine-5'-monophosphate Dehydrogenase 1
(Gene symbol: IMPDH1)
Molecule annotation
Chemicals and Non-standard biopolymers (40 molecules)
1
16
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
2
8
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
3
8
INOSINIC ACIDINOSINIC ACID
4
8
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303