8U6K: Crystal Structure of HIV-1 Reverse Transcriptase in Complex with N-(2-(2-((6-cyanonaphthalen-1-yl)oxy)phenoxy)ethyl)-N-methylacrylamide (JLJ747), a non-nucleoside inhibitor

PDB ID: 8U6KDownload
MMDB ID: 238345
PDB Deposition Date: 2023/9/13
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.72  Å
Source Organism:
Similar Structures:
Biological Unit for 8U6K: dimeric; determined by author and by software (PISA)
Molecular Components in 8U6K
Label Count Molecule
Proteins (2 molecules)
1
Reverse Transcriptase/ribonuclease H
Molecule annotation
1
P51 RT
(Gene symbol: gag-pol)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
N-(2-{2-[(6-cyanonaphthalen-1-yl)oxy]phenoxy}ethyl)-N-methylprop-2-enamideN-(2-{2-[(6-cyanonaphthalen-1-yl)oxy]phenoxy}ethyl)-N-methylprop-2-enamide
2
2
MAGNESIUM IONMAGNESIUM ION
3
1
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303