8U6F: Crystal Structure of HIV-1 Reverse Transcriptase in Complex with N-(2-(5-chloro-2-(3-chloro-5-cyanophenoxy)phenoxy)ethyl)-N-methylacrylamide (JLJ742), a non-nucleoside inhibitor

PDB ID: 8U6FDownload
MMDB ID: 238341
PDB Deposition Date: 2023/9/13
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.69  Å
Source Organism:
Similar Structures:
Biological Unit for 8U6F: dimeric; determined by author and by software (PISA)
Molecular Components in 8U6F
Label Count Molecule
Proteins (2 molecules)
1
Reverse Transcriptase/ribonuclease H
(Gene symbol: gag-pol)
Molecule annotation
1
P51 RT
(Gene symbol: gag-pol)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{2-[5-chloro-2-(3-chloro-5-cyanophenoxy)phenoxy]ethyl}-N-methylprop-2-enamideN-{2-[5-chloro-2-(3-chloro-5-cyanophenoxy)phenoxy]ethyl}-N-methylprop-2-enamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303