8U5I: Crystal Structure of human IDO1 bound to Compound 23

PDB ID: 8U5IDownload
MMDB ID: 255657
PDB Deposition Date: 2023/9/12
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.17  Å
Source Organism:
Similar Structures:
Biological Unit for 8U5I: dimeric; determined by author
Molecular Components in 8U5I
Label Count Molecule
Proteins (2 molecules)
2
Indoleamine 2,3-dioxygenase 1
(Gene symbol: IDO1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
2
(1R,2S)-8-(ethanesulfonyl)-2-[(4R,5S,9aM)-5H-imidazo[5,1-a]isoindol-5-yl]-8-azaspiro[4.5]decan-1-ol(1R,2S)-8-(ethanesulfonyl)-2-[(4R,5S,9aM)-5H-imidazo[5,1-a]isoindol-5-yl]-8-azaspiro[4.5]decan-1-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303