8U4T: Structure of tetrameric CXCR4 in complex with REGN7663 Fab

PDB ID: 8U4TDownload
MMDB ID: 244109
PDB Deposition Date: 2023/9/11
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.38  Å
Source Organism:
Similar Structures:
Biological Unit for 8U4T: dodecameric; determined by author
Molecular Components in 8U4T
Label Count Molecule
Proteins (12 molecules)
4
Regn7663 FAB Light Chain
Molecule annotation
4
Regn7663 FAB Heavy Chain
Molecule annotation
4
C-x-c Chemokine Receptor Type 4
(Gene symbol: CXCR4)
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
16
CHOLESTEROLCHOLESTEROL
2
4
(2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate(2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303