8U4S: Structure of trimeric CXCR4 in complex with REGN7663 Fab

PDB ID: 8U4SDownload
MMDB ID: 244108
PDB Deposition Date: 2023/9/11
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 3.35  Å
Source Organism:
Similar Structures:
Biological Unit for 8U4S: nonameric; determined by author
Molecular Components in 8U4S
Label Count Molecule
Proteins (9 molecules)
3
Regn7663 FAB Light Chain
Molecule annotation
3
Regn7663 FAB Heavy Chain
Molecule annotation
3
C-x-c Chemokine Receptor Type 4
(Gene symbol: CXCR4)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
6
CHOLESTEROLCHOLESTEROL
2
3
(2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate(2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303