8U4P: Structure of AMD3100-bound CXCR4/Gi complex

PDB ID: 8U4PDownload
MMDB ID: 244105
PDB Deposition Date: 2023/9/11
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.15  Å
Source Organism:
Similar Structures:
Biological Unit for 8U4P: tetrameric; determined by author
Molecular Components in 8U4P
Label Count Molecule
Proteins (4 molecules)
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
(Gene symbol: GNAI1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
1
C-x-c Chemokine Receptor Type 4
(Gene symbol: CXCR4)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
CHOLESTEROLCHOLESTEROL
2
1
PlerixaforPlerixafor
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303