8U4O: Structure of CXCL12-bound CXCR4/Gi complex

PDB ID: 8U4ODownload
MMDB ID: 244104
PDB Deposition Date: 2023/9/11
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 3.29  Å
Source Organism:
Similar Structures:
Biological Unit for 8U4O: pentameric; determined by author
Molecular Components in 8U4O
Label Count Molecule
Proteins (5 molecules)
1
C-x-c Chemokine Receptor Type 4
(Gene symbol: CXCR4)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
(Gene symbol: GNAI1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
1
Stromal Cell-derived Factor 1
(Gene symbol: CXCL12)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
CHOLESTEROLCHOLESTEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303