8U4L: Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain

PDB ID: 8U4LDownload
MMDB ID: 244102
PDB Deposition Date: 2023/9/10
Updated in MMDB: 2024/09
Experimental Method:
electron microscopy
Resolution: 3.31  Å
Source Organism:
Similar Structures:
Biological Unit for 8U4L: trimeric; determined by author
Molecular Components in 8U4L
Label Count Molecule
Proteins (3 molecules)
1
Isoform Jm-a Cyt-1 of Receptor Tyrosine-protein Kinase Erbb-4
(Gene symbol: ERBB4)
Molecule annotation
1
Receptor Tyrosine-protein Kinase Erbb-2
(Gene symbol: ERBB2)
Molecule annotation
1
Isoform 6 of Pro-neuregulin-1, Membrane-bound Isoform
(Gene symbol: NRG1)
Molecule annotation
Chemicals and Non-standard biopolymers (35 molecules)
1
23
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
8
beta-D-mannopyranosebeta-D-mannopyranose
3
4
alpha-D-mannopyranosealpha-D-mannopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303