8U2O: Crystal Structure of Cdk-related protein kinase 6 (PK6) from Plasmodium falciparum in complex with inhibitor TCMDC-123995

PDB ID: 8U2ODownload
MMDB ID: 236241
PDB Deposition Date: 2023/9/6
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.15  Å
Source Organism:
Similar Structures:
Biological Unit for 8U2O: dimeric; determined by author and by software (PISA)
Molecular Components in 8U2O
Label Count Molecule
Proteins (2 molecules)
2
Protein Kinase 6
(Gene symbol: PF3D7_1337100)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
SULFATE IONSULFATE ION
2
4
CHLORIDE IONCHLORIDE ION
3
2
GLYCEROLGLYCEROL
4
2
N-[(4P)-2-(4-chloroanilino)-4'-methyl[4,5'-bi-1,3-thiazol]-2'-yl]acetamideN-[(4P)-2-(4-chloroanilino)-4'-methyl[4,5'-bi-1,3-thiazol]-2'-yl]acetamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303