8U1F: FGFR2 Kinase Domain Bound to Irreversible Inhibitor Cmpd 10

PDB ID: 8U1FDownload
MMDB ID: 242699
PDB Deposition Date: 2023/8/31
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 3.33  Å
Source Organism:
Similar Structures:
Biological Unit for 8U1F: dimeric; determined by author and by software
Molecular Components in 8U1F
Label Count Molecule
Proteins (2 molecules)
2
Fibroblast Growth Factor Receptor 2
(Gene symbol: FGFR2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
GLYCEROLGLYCEROL
2
2
N-[4-(4-amino-7-methyl-5-{4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-2-methylpropanamideN-[4-(4-amino-7-methyl-5-{4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-2-methylpropanamide
3
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303