8U16: The ternary complex structure of DDB1-CRBN-SALL4(ZF1,2)-short bound to Pomalidomide

PDB ID: 8U16Download
MMDB ID: 240688
PDB Deposition Date: 2023/8/30
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 8U16: trimeric; determined by author and by software (PISA)
Molecular Components in 8U16
Label Count Molecule
Proteins (3 molecules)
1
Protein Cereblon
(Gene symbol: CRBN)
Molecule annotation
1
DNA Damage-binding Protein 1
(Gene symbol: DDB1)
Molecule annotation
1
Sal-like Protein 4
(Gene symbol: SALL4)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
3
ZINC IONZINC ION
2
1
S-PomalidomideS-Pomalidomide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303