8U02: CryoEM structure of D2 dopamine receptor in complex with GoA KE mutant and dopamine

PDB ID: 8U02Download
MMDB ID: 251267
PDB Deposition Date: 2023/8/28
Updated in MMDB: 2024/08
Experimental Method:
electron microscopy
Resolution: 3.28  Å
Source Organism:
Similar Structures:
Biological Unit for 8U02: tetrameric; determined by author
Molecular Components in 8U02
Label Count Molecule
Proteins (4 molecules)
1
D(2) Dopamine Receptor
(Gene symbol: DRD2)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(o) Subunit Alpha
(Gene symbol: GNAO1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
L-DOPAMINEL-DOPAMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303