8TZZ: SpG Cas9 with NGC PAM DNA target

PDB ID: 8TZZDownload
MMDB ID: 246187
PDB Deposition Date: 2023/8/28
Updated in MMDB: 2025/06
Experimental Method:
electron microscopy
Resolution: 3.56  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8TZZ: pentameric; determined by author
Molecular Components in 8TZZ
Label Count Molecule
Protein (1 molecule)
1
Crispr-associated Endonuclease Cas9/csn1
Molecule annotation
Nucleotides(4 molecules)
1
RNA (98-mer)
Molecule annotation
1
DNA (5'-d(p*cp*gp*tp*tp*tp*gp*tp*ap*cp*tp*gp*cp*ap*gp*cp*g)-3')
Molecule annotation
1
DNA (5'-d(p*tp*cp*tp*cp*ap*tp*cp*tp*tp*tp*ap*tp*gp*cp*gp*tp*c)-3')
Molecule annotation
1
DNA (5'-d(p*tp*gp*cp*ap*gp*tp*ap*cp*ap*ap*ap*cp*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
5
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303