8TXZ: Structure of C-terminal LRRK2 bound to MLi-2

PDB ID: 8TXZDownload
MMDB ID: 239519
PDB Deposition Date: 2023/8/24
Updated in MMDB: 2023/12
Experimental Method:
electron microscopy
Resolution: 3.05  Å
Source Organism:
Similar Structures:
Biological Unit for 8TXZ: monomeric; determined by author
Molecular Components in 8TXZ
Label Count Molecule
Protein (1 molecule)
1
Leucine-rich Repeat Serine/threonine-protein Kinase 2
(Gene symbol: LRRK2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
(2~{R},6~{S})-2,6-dimethyl-4-[6-[5-(1-methylcyclopropyl)oxy-1~{H}-indazol-3-yl]pyrimidin-4-yl]morpholine(2~{R},6~{S})-2,6-dimethyl-4-[6-[5-(1-methylcyclopropyl)oxy-1~{H}-indazol-3-yl]pyrimidin-4-yl]morpholine
2
1
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303