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8TXO: E. coli DNA-directed RNA polymerase transcription elongation complex bound to the unnatural dZ-PTP base pair in the active site

PDB ID:

MMDB ID:

241821

PDB Deposition Date:

2023/8/23

Updated in MMDB:

2024/11

Experimental Method:

electron microscopy

Resolution:

3.1 Å

Source Organism:

synthetic construct▼

Taxonomy	Molecule
synthetic construct	N, R, T
Escherichia coli	A, G, I, J

Similar Structures:

Biological Unit for 8TXO: heptameric; determined by author

Molecular Components in 8TXO
Label	Count	Molecule
Proteins (4 molecules)
A G	2	DNA-directed RNA Polymerase Subunit Alpha
I	1	DNA-directed RNA Polymerase Subunit Beta
J	1	DNA-directed RNA Polymerase Subunit Beta'
Nucleotides(3 molecules)
N	1	Non-template Single Stranded DNA
R	1	RNA Oligomer
T	1	Template Single Stranded DNA
Chemicals and Non-standard biopolymers (4 molecules)
1	2	ZINC ION
2	1	MAGNESIUM ION
3	1	[[(2~{R},3~{S},4~{R},5~{R})-5-(4-azanyl-2-oxidanylidene-1$l^{4},3,5,7-tetrazabicyclo[4.3.0]nona-1(6),3,8-trien-7-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate $[[(2~{R},3~{S},4~{R},5~{R})-5-(4-azanyl-2-oxidanylidene-1$l^{4},3,5,7-tetrazabicyclo[4.3.0]nona-1(6),3,8-trien-7-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate$

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Citing MMDB