8TTZ: Crystal structure of monkey TLR7 ectodomain with compound 20

PDB ID: 8TTZDownload
MMDB ID: 242420
PDB Deposition Date: 2023/8/15
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 3.14  Å
Source Organism:
Similar Structures:
Biological Unit for 8TTZ: dimeric; determined by author and by software (PISA)
Molecular Components in 8TTZ
Label Count Molecule
Proteins (2 molecules)
2
Toll-like Receptor 7
(Gene symbol: TLR7)
Molecule annotation
Chemicals and Non-standard biopolymers (49 molecules)
1
18
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
29
SULFATE IONSULFATE ION
3
2
(3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol(3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303