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Biotechnology Information

8TTW: Cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with temsavir, 8ANC195, and 10-1074

PDB ID:

MMDB ID:

238329

PDB Deposition Date:

2023/8/15

Updated in MMDB:

2023/11

Experimental Method:

electron microscopy

Resolution:

2.96 Å

Source Organism:

Human immunodeficiency virus 1▼

Taxonomy	Molecule
Human immunodeficiency virus 1	A, B, E, F, I, J
Homo sapiens	C, D, G, H, K, L, M, N, O, P, Q, R

Similar Structures:

Biological Unit for 8TTW: octadecameric; determined by author

Molecular Components in 8TTW
Label	Count	Molecule
Proteins (18 molecules)
A E I	3	Envelope Glycoprotein Gp160
B F J	3	Bg505 Sosip.664 Transmembrane Protein Gp41
C G K	3	Antibody 8anc195 Heavy Chain
D H L	3	Antibody 8anc195 Light Chain
M O Q	3	Antibody 10-1074 Heavy Chain
N P R	3	Antibody 10-1074 Light Chain
Chemicals and Non-standard biopolymers (162 molecules)
1	105	2-acetamido-2-deoxy-beta-D-glucopyranose
2	9	beta-D-mannopyranose
3	45	alpha-D-mannopyranose
4	3	1-[4-(benzenecarbonyl)piperazin-1-yl]-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione

* Click molecule labels to explore molecular sequence information.

Citing MMDB