8TRK: Cryo-EM structure of the rat P2X7 receptor in complex with the allosteric antagonist methyl blue

PDB ID: 8TRKDownload
MMDB ID: 253596
PDB Deposition Date: 2023/8/9
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 2.69  Å
Source Organism:
Similar Structures:
Biological Unit for 8TRK: trimeric; determined by author
Molecular Components in 8TRK
Label Count Molecule
Proteins (3 molecules)
3
P2X Purinoceptor 7
(Gene symbol: P2rx7)
Molecule annotation
Chemicals and Non-standard biopolymers (42 molecules)
1
3
4,4',4''-[methanetriyltris(4,1-phenyleneazanediyl)]tri(benzene-1-sulfonic acid)4,4',4''-[methanetriyltris(4,1-phenyleneazanediyl)]tri(benzene-1-sulfonic acid)
2
3
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
3
6
ZINC IONZINC ION
4
15
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
5
15
PALMITIC ACIDPALMITIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303