8TQW: Structure of human transcriptional Mediator complex

PDB ID: 8TQWDownload
MMDB ID: 253236
PDB Deposition Date: 2023/8/8
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 8.2  Å
Source Organism:
Similar Structures:
Biological Unit for 8TQW: 29-meric; determined by author and by software
Molecular Components in 8TQW
Label Count Molecule
Proteins (29 molecules)
1
Mediator of RNA Polymerase II Transcription Subunit 27
(Gene symbol: MED27)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 28
(Gene symbol: MED28)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 29
(Gene symbol: MED29)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 30
(Gene symbol: MED30)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 31
(Gene symbol: MED31)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 1
(Gene symbol: MED1)
Molecule annotation
1
Unknown Chain
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 4
(Gene symbol: MED4)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 6
(Gene symbol: MED6)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 7
(Gene symbol: MED7)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 8
(Gene symbol: MED8)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 9
(Gene symbol: MED9)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 10
(Gene symbol: MED10)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 11
(Gene symbol: MED11)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 14
(Gene symbol: MED14)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 15
(Gene symbol: MED15)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 16
(Gene symbol: MED16)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 17
(Gene symbol: MED17)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 18
(Gene symbol: MED18)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 19
(Gene symbol: MED19)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 20
(Gene symbol: MED20)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 21
(Gene symbol: MED21)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 22
(Gene symbol: MED22)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 23
(Gene symbol: MED23)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 24
(Gene symbol: MED24)
Molecule annotation
1
Cyclin-dependent Kinase 8
(Gene symbol: CDK8)
Molecule annotation
1
Cyclin-c
(Gene symbol: CCNC)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 12
(Gene symbol: MED12)
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 13
(Gene symbol: MED13)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303