8TOV: HIV-CA Disulfide linked Hexamer bound to Quinazolin-4-one Scaffold inhibitor

PDB ID: 8TOVDownload
MMDB ID: 240293
PDB Deposition Date: 2023/8/4
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 8TOV: hexameric; determined by author and by software (PISA)
Molecular Components in 8TOV
Label Count Molecule
Proteins (6 molecules)
6
Matrix Protein P17
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
6
2-[4-(4-aminobenzene-1-sulfonyl)-2-oxopiperazin-1-yl]-N-[(1R)-2-(3,5-difluorophenyl)-1-{3-[4-(morpholine-4-sulfonyl)phenyl]-4-oxo-3,4-dihydroquinazolin-2-yl}ethyl]acetamide2-[4-(4-aminobenzene-1-sulfonyl)-2-oxopiperazin-1-yl]-N-[(1R)-2-(3,5-difluorophenyl)-1-{3-[4-(morpholine-4-sulfonyl)phenyl]-4-oxo-3,4-dihydroquinazolin-2-yl}ethyl]acetamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303