8TNI: Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing bi-specific antibody CAP256L-R27 targeting the CD4-binding site and the V2-apex

PDB ID: 8TNIDownload
MMDB ID: 246537
PDB Deposition Date: 2023/8/1
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.61  Å
Source Organism:
Human immunodeficiency virus 1▼
Similar Structures:
Biological Unit for 8TNI: decameric; determined by author
Molecular Components in 8TNI
Label Count Molecule
Proteins (10 molecules)
3
Hiv-1 Bg505 Ds-sosip Gp120
Molecule annotation
3
Hiv-1 Bg505 Ds-sosip Gp41
Molecule annotation
3
Light Chain of Bi-specific Antibody Cap256l-r27
Molecule annotation
1
Heavy Chain of Bi-specific Antibody Cap256l-r27
Molecule annotation
Chemicals and Non-standard biopolymers (72 molecules)
1
66
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
5
beta-D-mannopyranosebeta-D-mannopyranose
3
1
alpha-D-mannopyranosealpha-D-mannopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303