8TK3: HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) having oxidized catalytic cysteine and complexed with 6-(difluoromethyl)pyrimidin-4-ol at two allosteric sites

PDB ID: 8TK3Download
MMDB ID: 251069
PDB Deposition Date: 2023/7/25
Updated in MMDB: 2024/08
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 8TK3: monomeric; determined by author and by software (PISA)
Molecular Components in 8TK3
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Protein Phosphatase 3
(Gene symbol: DUSP3)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
6-(difluoromethyl)pyrimidin-4-ol6-(difluoromethyl)pyrimidin-4-ol
2
3
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303