8TI4: monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface

PDB ID: 8TI4Download
MMDB ID: 238883
PDB Deposition Date: 2023/7/19
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 8TI4: dimeric; determined by author and by software (PISA)
Molecular Components in 8TI4
Label Count Molecule
Proteins (2 molecules)
1
Igg1 FAB Heavy Chain, Mutated to Promote Correct Pairing
Molecule annotation
1
Igg1 FAB Light Chain, Mutated for Better Pairing With Cognate Heavy Chain
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303