8TH4: Structure of AT118-L Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor and Losartan

PDB ID: 8TH4Download
MMDB ID: 247317
PDB Deposition Date: 2023/7/13
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8TH4: tetrameric; determined by author
Molecular Components in 8TH4
Label Count Molecule
Proteins (4 molecules)
1
Type-1 Angiotensin II Receptor Soluble Cytochrome B562 Complex
(Gene symbol: AGTR1)
Molecule annotation
1
Bag2 Anti-bril FAB Heavy Chain
Molecule annotation
1
Bag2 Anti-bril FAB Light Chain
Molecule annotation
1
At118-l Nanobody
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
[2-butyl-5-chloranyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol[2-butyl-5-chloranyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303