8TE3: Crystal structure of the methyltransferase domain of R882C/R676K DNMT3A homotetramer

PDB ID: 8TE3Download
MMDB ID: 244064
PDB Deposition Date: 2023/7/5
Updated in MMDB: 2024/09
Experimental Method:
x-ray diffraction
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 8TE3: tetrameric; determined by author
Molecular Components in 8TE3
Label Count Molecule
Proteins (4 molecules)
4
DNA (Cytosine-5)-methyltransferase 3A
(Gene symbol: DNMT3A)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303