8TB8: Sequence specific (AATT) orientation of Hoechst molecules at a unique minor groove binding site (position1) within a self-assembled 3D DNA lattice (4x5)

PDB ID: 8TB8Download
MMDB ID: 240281
PDB Deposition Date: 2023/6/28
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.95  Å
Source Organism:
Biological Unit for 8TB8: tetrameric; determined by author
Molecular Components in 8TB8
Label Count Molecule
Nucleotides(4 molecules)
1
DNA (5'-d(*gp*ap*cp*ap*ap*tp*tp*gp*cp*tp*gp*ap*cp*gp*ap*cp*ap*cp*tp*cp*a*(ht1))-3')
Molecule annotation
1
DNA (5'-d(p*cp*gp*tp*cp*a)-3')
Molecule annotation
1
DNA (5'-d(*tp*cp*tp*gp*ap*gp*tp*gp*t)-3')
Molecule annotation
1
DNA (5'-d(p*gp*cp*ap*ap*tp*tp*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
1
2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303