8T7D: Crystal structure of wild type IDH1 bound to compound 1

PDB ID: 8T7DDownload
MMDB ID: 251452
PDB Deposition Date: 2023/6/20
Updated in MMDB: 2024/09
Experimental Method:
x-ray diffraction
Resolution: 3.444  Å
Source Organism:
Similar Structures:
Biological Unit for 8T7D: dimeric; determined by author and by software (PISA)
Molecular Components in 8T7D
Label Count Molecule
Proteins (2 molecules)
2
Isocitrate Dehydrogenase [nadp] Cytoplasmic
(Gene symbol: IDH1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-(4-tert-butylphenyl)-7,8-dimethyl-5,11-dihydro-6H-pyrido[2,3-b][1,5]benzodiazepine-6-carboxamideN-(4-tert-butylphenyl)-7,8-dimethyl-5,11-dihydro-6H-pyrido[2,3-b][1,5]benzodiazepine-6-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303