8T75: Crystal Structure of KRAS4a (GMPPNP) in complex with RAF1 (RBD-CRD)

PDB ID: 8T75Download
MMDB ID: 242688
PDB Deposition Date: 2023/6/19
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.65  Å
Source Organism:
Similar Structures:
Biological Unit for 8T75: dimeric; determined by author
Molecular Components in 8T75
Label Count Molecule
Proteins (2 molecules)
1
Gtpase Kras
(Gene symbol: KRAS)
Molecule annotation
1
RAF Proto-oncogene Serine/threonine-protein Kinase
(Gene symbol: RAF1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
2
1
MAGNESIUM IONMAGNESIUM ION
3
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303