8T6L: Cryo-EM structure of rat cardiac sodium channel NaV1.5 with batrachotoxin analog BTX-B

PDB ID: 8T6LDownload
MMDB ID: 243744
PDB Deposition Date: 2023/6/16
Updated in MMDB: 2024/04
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8T6L: monomeric; determined by author and by software
Molecular Components in 8T6L
Label Count Molecule
Protein (1 molecule)
1
Sodium Channel Protein Type 5 Subunit Alpha,green Fluorescent Protein
(Gene symbol: Scn5a)
Molecule annotation
Chemicals and Non-standard biopolymers (41 molecules)
1
11
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
beta-D-mannopyranosebeta-D-mannopyranose
3
3
alpha-D-mannopyranosealpha-D-mannopyranose
4
10
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
5
11
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
6
2
(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en
7
2
(1R)-1-[(5aR,7aR,9R,11aS,11bS,12R,13aR)-9,12-dihydroxy-2,11a-dimethyl-1,2,3,4,7a,8,9,10,11,11a,12,13-dodecahydro-7H-9,11b-epoxy-13a,5a-prop[1]enophenanthro[2,1-f][1,4]oxazepin-14-yl]ethyl benzoate(1R)-1-[(5aR,7aR,9R,11aS,11bS,12R,13aR)-9,12-dihydroxy-2,11a-dimethyl-1,2,3,4,7a,8,9,10,11,11a,12,13-dodecahydro-7H-9,11b-epoxy-13a,5a-prop[1]enophenanthro[2,1-f][1,4]oxazepin-14-yl]ethyl benzoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303