8T68: Crystal Structure of the SET Domain of Human Histone-Lysine N-Methyltransferase SUV420H1 in complex with RQ3-111

PDB ID: 8T68Download
MMDB ID: 255655
PDB Deposition Date: 2023/6/15
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 8T68: monomeric; determined by author
Molecular Components in 8T68
Label Count Molecule
Protein (1 molecule)
1
Histone-lysine N-methyltransferase Kmt5b
(Gene symbol: KMT5B)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC IONZINC ION
2
1
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
3
1
6,7-dichloro-N-[(3R)-oxolan-3-yl]-4-(pyridin-4-yl)phthalazin-1-amine6,7-dichloro-N-[(3R)-oxolan-3-yl]-4-(pyridin-4-yl)phthalazin-1-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303