8T5I: Crystal structure of human WDR5 in complex with MR4397

PDB ID: 8T5IDownload
MMDB ID: 233984
PDB Deposition Date: 2023/6/13
Updated in MMDB: 2023/08
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 8T5I: monomeric; determined by author
Molecular Components in 8T5I
Label Count Molecule
Protein (1 molecule)
1
WD Repeat-containing Protein 5
(Gene symbol: WDR5)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
N-[(2S)-1-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)-1-oxopentan-2-yl]-3-[(1H-imidazol-1-yl)methyl]benzamideN-[(2S)-1-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)-1-oxopentan-2-yl]-3-[(1H-imidazol-1-yl)methyl]benzamide
2
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
Molecule information is not available.
4
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303