8T3O: Cryo-EM structure of the TUG-891 bound FFA4-Gq complex

PDB ID: 8T3ODownload
MMDB ID: 241480
PDB Deposition Date: 2023/6/7
Updated in MMDB: 2025/05
Experimental Method:
electron microscopy
Resolution: 3.06  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 8T3O: pentameric; determined by author
Molecular Components in 8T3O
Label Count Molecule
Proteins (5 molecules)
1
Free Fatty Acid Receptor 4
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Guanine Nucleotide-binding Protein G(q)
Molecule annotation
1
Scfv16
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid
2
1
(2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate(2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
3
1
PALMITIC ACIDPALMITIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303