8T1V: Crystal structure of orphan G protein-coupled receptor 6 with bound inverse agonist 3h

PDB ID: 8T1VDownload
MMDB ID: 255958
PDB Deposition Date: 2023/6/4
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 8T1V: dimeric; determined by author
Molecular Components in 8T1V
Label Count Molecule
Proteins (2 molecules)
2
G-protein Coupled Receptor 6, Soluble Cytochrome B562 Chimera
(Gene symbol: GPR6)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
3-{4-[(2,4-difluorophenyl)methyl]piperazin-1-yl}-7-methyl-N-(propan-2-yl)pyrido[3,4-b]pyrazin-2-amine3-{4-[(2,4-difluorophenyl)methyl]piperazin-1-yl}-7-methyl-N-(propan-2-yl)pyrido[3,4-b]pyrazin-2-amine
2
2
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303