8SZE: Crystal structure of Yersinia pestis dihydrofolate reductase in complex with Trimethoprim

PDB ID: 8SZEDownload
MMDB ID: 231258
PDB Deposition Date: 2023/5/29
Updated in MMDB: 2023/06
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8SZE: monomeric; determined by author
Molecular Components in 8SZE
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
TRIMETHOPRIMTRIMETHOPRIM
2
3
SULFATE IONSULFATE ION
3
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
3
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303