8SYC: Crystal structure of PDE3B in complex with GSK4394835A

PDB ID: 8SYCDownload
MMDB ID: 242395
PDB Deposition Date: 2023/5/25
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 8SYC: dimeric; determined by author
Molecular Components in 8SYC
Label Count Molecule
Proteins (2 molecules)
2
Cgmp-inhibited 3',5'-cyclic Phosphodiesterase 3B
(Gene symbol: PDE3B)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
2
[3-[(4,7-dimethoxyquinolin-2-yl)carbonylamino]-5-[methyl-(phenylmethyl)carbamoyl]phenyl]-oxidanyl-oxidanylidene-boron[3-[(4,7-dimethoxyquinolin-2-yl)carbonylamino]-5-[methyl-(phenylmethyl)carbamoyl]phenyl]-oxidanyl-oxidanylidene-boron
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303